Strain Data Sheet

RBRC09541

Strain Information

Image
BRC No.RBRC09541
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameC57BL/6N-Fdx2<em1Rbrc>
Former Common nameC57BL/6N-Fdx1l<em1Rbrc>
H-2 Haplotype
ES Cell line
Background strainC57BL/6NJcl
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Fdx2
MGI:1915415		ferredoxin 29Fdx2<em1Rbrc>
MGI:6156129		endonuclease mediated mutation 1, RIKEN BRC

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal behavior(MP:0004924)

  • decreased circulating creatine kinase level(MP:0010091)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT should acknowledge RIKEN BRC and the International Mouse Phenotyping Consortium for creating and providing of the knockout mice.
    DepositorRIKEN BRC (RIKEN BRC)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    Zhang J, Zhang Y, Mohibi S, Perng V, Bustamante M, Shi Y, Nakajima K, Chen M, Chen X.
    Ferredoxin 2 is critical for tumor suppression and lipid homeostasis but dispensable for embryonic development.
    Am J Pathol (2024) 39732391