Strain Data Sheet

RBRC09566

Strain Information

Image
BRC No.RBRC09566
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Ick<tm1.1Tfur>
Former Common nameICK flox mice
H-2 Haplotype
ES Cell lineTC1 [129S6/SvEvTac]
Background strainC57BL/6JJcl
Appearance
Strain development
Strain description
Colony maintenance
References
ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport.
Chaya T, Omori Y, Kuwahara R, Furukawa T
EMBO J., 33(11):1227-1242 (2014). 24797473

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site9Frt
Ick
MGI:1934157		intestinal cell kinase9Ick<tm1.1Tfur> targeted mutation 1, Takahisa Furukawa
  • endocrine-cerebro-osteodysplasia syndrome(DisGeNET, MedGEN)

  • epilepsy, juvenile myoclonic, susceptibility to, 10(MedGEN)
    • loxP phage P1 loxP9loxP
    loxP phage P1 loxP9loxP

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAPhage P1 loxP sites, yeast FRT (flipase recombination target) site, mouse Ick genomic DNA
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J., 33(11):1227-1242 (2014). Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University).　The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.
    DepositorTakahisa Furukawa (Osaka University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data