Strain Data Sheet

RBRC09811

Strain Information

Image
BRC No.RBRC09811
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.Cg-Pcdha<tm>/TyagRbrc
Former Common namedelta Pcdha
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Pcdha
MGI:3719085		protocadherin alpha cluster18Pcdha
loxP phage P1 loxP18loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal cingulate gyrus morphology(MP:0004167)

  • abnormal dentate gyrus morphology(MP:0000812)

  • abnormal dorsal striatum morphology(MP:0004102)

  • abnormal entorhinal cortex morphology(MP:0006300)

  • abnormal globus pallidus morphology(MP:0004081)
    • more 12 phenotypes
  • abnormal hippocampus morphology(MP:0000807)

  • abnormal lateral geniculate nucleus morphology(MP:0004165)

  • abnormal olfactory bulb morphology(MP:0000819)

  • abnormal primary motor cortex morphology(MP:0012448)

  • abnormal serotonergic neuron morphology(MP:0003877)

  • abnormal substantia nigra morphology(MP:0000836)

  • abnormal thalamus morphology(MP:0000832)

  • decreased body weight(MP:0001262)

  • increased grooming behavior(MP:0001441)

  • increased serotonin level(MP:0010069)

  • nervous system phenotype(MP:0003631)

  • skin lesions(MP:0001212)
    • Detailed phenotype data

    Ordering Information

    Donor DNAphage P1 loxP site, mouse Pcdha genomic DNA
    Research applicationCre/loxP system
    Specific Term and ConditionsIf the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR.
    DepositorTakeshi Yagi (Osaka University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data