Strain Data Sheet

RBRC09865

Strain Information

Image
BRC No.RBRC09865
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;B6129-Cbx2<tm1.1Hko>
Former Common nameCbx2(M33)cond.
H-2 Haplotype
ES Cell lineM1 [(C57BL/6 x 129)F1]
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Haruhiko Koseki, RIKEN, in 2011. M1(B6/129 ) ES cells were used. This strain was backcrossed to C57BL/6J twice.
Strain descriptionFloxed Cbx2 (chromobox 2) mice. A pair of loxP flanks Exon 3.
Colony maintenance
References

Health Report

Examination Date / Room / Rack2023/12/11Room:3-2Rack:ASentinel mouse program
2023/09/11Room:3-2Rack:ASentinel mouse program
2023/06/26Room:3-2Rack:AAdditional tests
2023/06/13Room:3-2Rack:ASentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cbx2
MGI:88289
chromobox 211Cbx2<tm1.1Hko> targeted mutation 1.1, Haruhiko Koseki
  • 46,XY sex reversal 5(MedGEN)
  • Frt-F5 yeast FRT (flippase recombination target) site, variant (F5)11Frt-F5
    loxP phage P1 loxP11loxP
    loxP phage P1 loxP11loxP

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
  • Detailed phenotype data

    Ordering Information

    Donor DNAyeast FRT-F5 (flipase recombination target) site, Phage P1 loxP sites, mouse Cbx2 genomic DNA
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsRECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorHaruhiko Koseki (RIKEN)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data