Strain Information | |
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Image | |
BRC No. | RBRC09898 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(CAG-Aldh2<*>E504K)02Oht |
Former Common name | DAL02 mice |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Shigeo Ohta, Nippon Medical School in 2009. A transgenic construct was injected into fertilized eggs derived from C57BL/6. This line was maintained in C57BL/6N background. |
Strain description | Transgenic mice overexpressing mutated Aldh2 (E504K) under the control of the CAG promoter. This mutated Aldh2 acts in a dominant-negative manner. |
Colony maintenance | |
References | Circ Res., 105, 1118-1127(2009). 19815821 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Aldh2aldehyde dehydrogenase 2, mitochondrialUNAldh2CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) |
Ordering Information | |
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Donor DNA | Chicken βactin -promoter, Mouse 改変型ALDH2, Rabbit β―Globin PolyA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Circ Res., 105, 1118-1127(2009).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Shigeo Ohta (Nippon Medical School) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |