Strain Data Sheet

RBRC10055

Strain Information

Image
BRC No.RBRC10055
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6(Cg)-Aqp1<tm1.1Tsna>
Former Common nameAQP1 KO
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strain
Appearance
Strain developmentDeveloped by Mika Tsujita, Brain Research Institute, Niigata University. RENKA ES cells derived from C57BL/6 were used to generate a strain (RBRC10056) harboring a floxed Aqp1 allele with the neo resistance gene. By crossing with a TLCN Cre mouse strain, exon 2, 3 and neo were deleted. C57BL/6 genetic background.
Strain descriptionAqp1 (aquaporin 1) knockout mice.
Colony maintenance
References
Virchow-Robin space and aquaporin-4: new insights on an old friend.
Nakada T
Croat. Med. J., 55(4), 328-336 (2014). 25165047

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Aqp1
MGI:103201		aquaporin 16Aqp1<tm1.1Tsna> targeted mutation 1.1, Tsutomu Nakada
loxP phage P1 loxP6loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • no abnormal phenotype detected(MP:0002169)
    • Detailed phenotype data

    Ordering Information

    Donor DNA合成核酸（バクテリオファージP1） loxP配列
    Research applicationCre/loxP system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Croat. Med. J., 55(4), 328-336 (2014).
    DepositorMika Terumitsu-Tsujita (Niigata University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data