Strain Data Sheet

RBRC10062

Strain Information

Image
BRC No.RBRC10062
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameC57BL/6J-F9<em1Tsuka>
Former Common nameF9 knockout mice (CRISPR/Cas9)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Tsukasa Ohmori, Jichi Medical University. C57BL/6J background.
Strain descriptionF9 (coagulation factor IX) mutant mice. F9 activity is less than 1% in homozygous mice. Deleted sequence: ATATACTAAGGTTTCCCGGTACGTCAACTGGATTAA.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
F9
MGI:88384		coagulation factor IXXF9<em1Tsuka> endonuclease-mediated mutation 1, Tsukasa Ohmori
  • hemophilia B(DisGeNET, MedGEN)

  • thrombophilia, X-linked, due to factor 9 defect(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationMouse Models for Human Disease
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorTsukasa Ohmori (Jichi Medical University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-
    Mouse of the Month Jun 2019

    BRC mice in Publications

    No Data