Strain Data Sheet

RBRC10156

Strain Information

Image
BRC No.RBRC10156
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameGomafu null Neo+(Acc.No.CDB1347K)
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine.
Ip J Y, Sone M, Nashiki C, Pan Q, Kitaichi K, Yanaka K, Abe T, Takao K, Miyakawa T, Blencowe B J, Nakagawa S
Sci. Rep., 6:27204 (2016). 27251103

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site5Frt
Miat
MGI:2444886		myocardial infarction associated transcript (non-protein coding)5Miat
loxP phage P1 loxP5loxP
neo neomycin resistance gene (E. coli)5 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal behavioral response to methamphetamine(MP:0012733)

  • hyperactivity(MP:0001399)

  • increased nervous system dopamine level(MP:0020876)
    • Detailed phenotype data

    Ordering Information

    Donor DNAマウスPGKプロモーター配列, 大腸菌ネオマイシン耐性遺伝子, マウスPGK polyAシグナル領域, 出芽酵母FRT配列, P1ファージloxP配列
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 6:27204 (2016).(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Shinichi Nakagawa (nakagawas@pharm.hokudai.ac.jp)) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. (CDB1347K) and Web Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Sci. Rep., 6:27204 (2016).) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
    DepositorRIKEN CDB (RIKEN CDB)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data