Strain Data Sheet
RBRC10157
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC10157 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | Gomafu null Neo-(Acc.No.CDB1377K) |
| Former Common name | Gomafu null Neo-(Acc.No.CDB1377K) |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Gomafu lncRNA knockout mice exhibit mild hyperactivity with enhanced responsiveness to the psychostimulant methamphetamine. Ip J Y, Sone M, Nashiki C, Pan Q, Kitaichi K, Yanaka K, Abe T, Takao K, Miyakawa T, Blencowe B J, Nakagawa S Sci. Rep., 6:27204 (2016). 27251103 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Miat MGI:2444886 | myocardial infarction associated transcript (non-protein coding) | 5 | Miat<tm1Shna> MGI:6148230 | targeted mutation 1, Shinichi Nakagawa | |||
| loxP | phage P1 loxP | 5 | loxP | ||||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | Phage P1 loxP site, mouse Miat genomic DNA |
| Research application | Cre/loxP system |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 6:27204 (2016). (1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Shinichi Nakagawa (nakagawas@pharm.hokudai.ac.jp)) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. (CDB1377K) and Web Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Sci. Rep., 6:27204 (2016).) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
| Depositor | RIKEN CDB (RIKEN CDB) |
| Strain Status |  Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
|---|
Peng KL, Vasudevan HN, Lockney DT, Baum R, Hendrickson RC, Raleigh DR, Schmitt AM. Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance. Proc Natl Acad Sci U S A 119(37) e2203738119(2022) 36067288 |