Strain Data Sheet

RBRC10272

Strain Information

Image
BRC No.RBRC10272
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6J-Tg(Fabp4-SOD1)1Ish
Former Common nameaP2-SOD1 Tg
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Iichiro Shimomura and his colleagues, Graduate School of Medicine, Osaka University in 2008. C57BL/6J genetic background.
Strain descriptionTransgenic mice expressing human SOD1 (superoxide dismutase 1, soluble) under the control of Fabp4 (fatty acid binding protein 4, adipocyte) promoter.
Colony maintenance
References
Oxidative Stress Inhibits Healthy Adipose Expansion Through Suppression of SREBF1-Mediated Lipogenic Pathway.
Okuno Y, Fukuhara A, Hashimoto E, Kobayashi H, Kobayashi S, Otsuki M, Shimomura I
Diabetes. 2018;67(6):1113-1127. 29618580

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
HBB2 rabbit beta-globin polyAUNHBB2
SOD1 superoxide dismutase 1, soluble (human)UNSOD1 mouse Fabp4 promoter

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse fatty acid binding protein 4 (Fabp4), adipocyte promoter, human SOD1 cDNA, rabbit beta-globin polyA
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Diabetes. 2018;67(6):1113-1127.For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach a written agreement on terms and conditions of use of it with Osaka University. The RECIPIENT must contact Osaka University and have a mutual consent in the case of application for any patents or commercial use based on the results from the use of the　BIOLOGICAL RESOURCE.
    DepositorIichiro Shimomura (Osaka University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data