Strain Information | |
---|---|
Image | |
BRC No. | RBRC10318 |
Type | Targeted Mutation Congenic![]() |
Species | Mus musculus |
Strain name | B6;Cg-Kat5<tm1.1Hko> |
Former Common name | Tip60 |
H-2 Haplotype | |
ES Cell line | M1 [(C57BL/6 x 129)F1] |
Background strain | C57BL/6NCrl |
Appearance | |
Strain development | Developed by Haruhiko Koseki, RIKEN and Issay Kitabayash, National Cancer Center Research Institute in 2013. M1 ((129 x C57BL/6)F1) ES cells were used. This strain was backcrossed to C57BL/6J twice. A neo cassette was removed by crossing a Flp mouse strain. |
Strain description | Kat5 (K(lysine) acetyltransferase 5) flox mouse. A pair of loxP flank exon 10 and 11 of the Kat5. |
Colony maintenance | |
References | EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice. Dong Y, Isono K I, Ohbo K, Endo T A, Ohara O, Maekawa M, Toyama Y, Ito C, Toshimori K, Helin K, Ogonuki N, Inoue K, Ogura A, Yamagata K, Kitabayashi I, Koseki H Mol. Cell. Biol., 37(19), e00082-17 (2017). 28694333 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |||||||
---|---|---|---|---|---|---|---|
Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Frt | yeast FRT (flippase recombination target) site | 19 | Frt | ||||
Kat5 MGI:1932051 | K(lysine) acetyltransferase 5 | 19 | Kat5<tm1.1Hko> | targeted mutation 1.1, Haruhiko Koseki | |||
loxP | phage P1 loxP | 19 | loxP |
Phenotype | |
---|---|
Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
---|---|
Donor DNA | 酵母 FRT配列, バクテリオファージP1 loxP |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Haruhiko Koseki (RIKEN) |
Strain Status | ![]() |
Strain Availability | ![]() |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |