Strain Data Sheet

RBRC10423

Strain Information

Image
BRC No.RBRC10423
TypeCRISPR/Cas9 (Transgene)Cartagena
SpeciesMus musculus
Strain nameC57BL/6N-Nmrk2<em7Sato>
Former Common nameNmrk2 floxed
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strainC57BL/6NCrSlc
Appearance
Strain developmentDeveloped by Thomas N. Sato, Advanced Telecommunications Research Institute International, in 2017. This strain was generated by the CRISPR/Cas9 using RENKA ES cells derived from C57BL/6N. C57BL/6N genetic background.
Strain descriptionNmrk2 (nicotinamide riboside kinase 2) floxed mice. A pair of loxP flanks a genomic fragment from Exon 2 to Exon 8.
Colony maintenance
References

Health Report

Examination Date / Room / Rack2025/01/07Room:3-ARack:FSentinel mouse program
2024/10/07Room:3-ARack:FSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Nmrk2
MGI:1916814		nicotinamide riboside kinase 210Nmrk2<em7Sato> endonuclease mediated mutation 7, Thomas N. Sato
loxP phage P1 loxP10loxP
loxP phage P1 loxP10loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAphage P1 loxP sites
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorThomas N. Sato (Advanced Telecommunications Research Institute International (ATR))
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data