Strain Data Sheet
RBRC10579
Strain Information | |
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| Image | |
| BRC No. | RBRC10579 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | C57BL/6N-Adrm1<tm1.2Smta> |
| Former Common name | Rpn13f/ f |
| H-2 Haplotype | |
| ES Cell line | RENKA [C57BL/6NCrlCrlj] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Jun Hamazaki, The University of Tokyo in 2009. RENKA ES cells derived from C57BL/6N were used. Mice were further backcrossed to C57BL/6N for more than 6 generations. |
| Strain description | Adrm1 (adhesion regulating molecule 1, Rpn13 Rpn13) floxed mice. A pair of loxP flanks exon 3 and 4 of the Adrm1 gene. An FRT-flanked Neo gene was deleted by crossing with a Flp-mouse strain. |
| Colony maintenance | |
| References | Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. Hamazaki J, Hirayama S, Murata S PLoS Genet. 2015 Jul 29;11(7):e1005401 26222436 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Adrm1 MGI:1929289 | adhesion regulating molecule 1 26S proteasome ubiquitin receptor | 2 | Adrm1<tm1.2Smta> | targeted mutation 1.2, Shigeo Murata | |||
| Frt | yeast FRT (flippase recombination target) site | 2 | Frt | ||||
| loxP | phage P1 loxP | 2 | loxP | ||||
| loxP | phage P1 loxP | 2 | loxP | ||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | Phage 1oxP sites, Yeast FRT (flippase recombination target) site, mouse Adrm1 genomic DNA |
| Research application | Cre/loxP system FLP/frt system |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Hamazaki J, Hirayama S, Murata S. (2015) Redundant roles of Rpn10 and Rpnl3 in recognition of ubiquitinated proteins and cellular homeostasis . PLoS Genet.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
| Depositor | Shigeo Murata (The University of Tokyo) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |