Strain Data Sheet

RBRC10603

Strain Information

Image
BRC No.RBRC10603
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Chn1<tm1Ito>
Former Common namealpha Chn-flox
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strain
Appearance
Strain developmentDeposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. MS12 ES cells derived from C57BL6, and then mice were crossed to C57BL/6J.
Strain descriptionChn1 (chimerin 1) floxed mice. A pair of loxP flanks Exon 9 and Exon10 of the Chn1.
Colony maintenance
References
RacGAP alpha2-chimaerin function in development adjusts cognitive ability in adulthood.
Iwata R, Ohi K, Kobayashi Y, Masuda A, Iwama M, Yasuda Y, Yamamori H, Tanaka M, Hashimoto R, Itohara S, Iwasato T
Cell Rep., 8(5) 1257-1264 (2014). 25159148

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Chn1
MGI:1915674		chimerin 12Chn1<tm1Ito>
MGI:5614423		targeted mutation 1, Shigeyoshi Itohara
  • Duane retraction syndrome 2(MedGEN)
    • Frt yeast FRT (flippase recombination target) site2Frt
    loxP phage P1 loxP2loxP
    loxP phage P1 loxP2loxP

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAPhage P1 loxP sites, yeast FRT (flipase recombination target) site, mouse Chn1 genomic DNA
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Rep., 8(5) 1257-1264 (2014).
    DepositorShigeyoshi Itohara (RIKEN CBS)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data