Strain Data Sheet

RBRC10617

Strain Information

Image
BRC No.RBRC10617
TypeCRISPR/Cas9 (Transgene)Cartagena
SpeciesMus musculus molossinus
Strain nameMSM-Del(6D6Mit188-D6Mit22)39Arak/Yuwa
Former Common nameMSM-de1Ch6-39
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Yuichi Wakabayashi, Chiba Cancer Center, in 2018. Developed by Kimi Araki, Kumamoto University using ES cells derived from MSM. CRISPR/Cas9 deleted Stmm4 loci (D6Mit188-D6Mit22).
Strain descriptionA mutant (Line 39) on MSM background deleting Stmm3 loci (D6Mit188-D6Mit22). Heterozygous mice are grossly normal. Viability of homozygous mutants is unknown.
Colony maintenance
References
Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms.
Okumura K, Sato M, Saito M, Miura I, Wakana S, Mao J H, Miyasaka Y, Kominami R, Wakabayashi Y
Carcinogenesis, 33 (11), 2260-2268 (2012). 22843548

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Suclg1
MGI:1927234		succinate-CoA ligase, GDP-forming, alpha subunit6Suclg1
  • mitochondrial DNA depletion syndrome 9(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAhuman Actin promoter, E.coli Neomycin resistant gene, SV40 polyA addition signal
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
    DepositorYuichi Wakabayashi (Chiba Cancer Center)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data