Strain Information | |
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Image | |
BRC No. | RBRC10662 |
Type | CRISPR/Cas9![]() |
Species | Mus musculus |
Strain name | B6;BDF1-Lrtm1<em1Tfur> |
Former Common name | Lrtm1 KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Takahisa Furukawa, Osaka University in 2017. The strain was generated by the CRISPR/Cas9 using BDF1 fertilized eggs. Mixed genetic background. |
Strain description | Lrtm1 (leucine-rich repeats and transmembrane domains 1) mutant mice. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Lrtm1 MGI:2442106 | leucine-rich repeats and transmembrane domains 1 | 14 | Lrtm1<em1Tfur> | endonuclease-mediated mutation 1, Takahisa Furukawa |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | pX330-U6-Chimeric_BB-CBh-hSpCas9[human U6 promoter, S. pyogenes gRNA scaffold, human U6 terminator, CMV,chicken hybrid CMV enhancer/chicken beta-actin promoter (CBh), Synthetic DNA 3xFLAG, SV40 nuclear localization signal(NLS), Streptococcus pyogenes SpCas9 (human codon-optimized), bovine GH polyA signal, AAV2 inverted terminal repeat (ITR), f1 phage f1 origin, E. coli Ampicillin resistance gene (AmpR), E. coli pUC origin] |
Research application | |
Specific Term and Conditions | In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. RECIPIENT which wants to use the BIOLOGICAL RESOURCE is requested to contact the depositor (Dr. Takahisa Furukawa) and enter into a Material Transfer Agreement with Osaka University. |
Depositor | Takahisa Furukawa (Osaka University) |
Strain Status | ![]() |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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No Data |