Strain Information | |
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Image | |
BRC No. | RBRC10783 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | C57BL/6N-Cdx2<tm1.1(P2A/mCherry/NLS)Card> |
Former Common name | Cdx2-mCherry |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Michihiko Sugimoto and Kimi Araki at Card, Kumamoto University in 2018. 6NK-7 ES cells derived from C57BL/6N were used to generate this strain. C57BL/6N genetic background. |
Strain description | Knockin mice in which P2A-mCherry-SV40NLS was inserted at the 3’ terminal of Cdx2 protein coding sequence. Homozygotes are viable and fertile. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Cdx2 MGI:88361 | caudal type homeobox 2 | 5 | Cdx2<tm1.1(P2A/mCherry/NLS)Card> | targeted mutation 1.1, Center for Animal Resources & Development | |||
P2A | porcine teschovirus-1 2A peptide | 5 | P2A | ||||
loxP | phage P1 loxP | 5 | loxP | ||||
mCherry | Red Fluorescent Protein (Discosoma sp.) | 5 | mCherry | ||||
nls | SV40 large T antigen nuclear localization signal (NLS) | 5 | nls |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | P2A (porcine teschovirus-1 2A peptide), mCherry cDNA (Red Fluorescent Protein (Discosoma sp.)), SV40 large T antigen nuclear localization signal (NLS), phage P1 loxP site, mouse Cdx2 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 本系統を用いて公表された第一報の論文In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent form the DEPOSITOR. |
Depositor | Kimi Araki (Kumamoto University) |
Strain Status | ![]() ![]() |
Strain Availability | ![]() Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |