Strain Information | |
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Image | |
BRC No. | RBRC10854 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Ctsc<tm1.1Ike> |
Former Common name | CatC tetO knockin |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | |
Appearance | |
Strain development | Developed by Kazuhiro Ikenaka at National Institute for Physiological Sciences in collaboration with Kenji Sakimura at Niigata University. RENKA ES cells derived from C57BL/6N were used to generate this strain. C57BL/6N background. Homozygous mice are viable and fertile. |
Strain description | Knockin mice in which a STOP-tetO cassette was placed upstream of the translation initiation site of the Ctsc (Cathepsin C) gene.Inserted DNA cassette contains loxP-FRT-Neo-poly A-FRT-tetO-loxP. Frt-flanked Neo-polyA cassette was removed by Flp. |
Colony maintenance | |
References | Glia. 2017 Jun;65(6):917-930. 28251676 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site7Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP |
Ordering Information | |
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Donor DNA | 大腸菌 tetracycline operator site 酵母 FRT CMV 最小プロモーター バクテリオファージP1 loxP |
Research application | Cre/loxP system FLP/frt system Tet system |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Nobuhiko Ohno (National Institute for Physiological Sciences) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |