Strain Data Sheet

RBRC10881

Strain Information

Image
BRC No.RBRC10881
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6J-Tg(CAG-EGFP,-TAp63c)1Taks
Former Common nameCAG-EGFP-TAp63 gamma
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Taku Saito at the Universtigy of Tokyo in 2011. C57BL/6J background.
Strain descriptionTransgenic mice expressing TAp63 gamma under the control of CAG promoter and Cre recombinase.
Colony maintenance
References
Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63.
Taniguchi Y, Kawata M, Ho Chang S, Mori D, Okada K, Kobayashi H, Sugita S, Hosaka Y, Inui H, Taketomi S, Yano F, Ikeda T, Akiyama H, Mills A A, Chung U I, Tanaka S, Kawaguchi H, Saito T
Arthritis Rheumatol., 69(3):598-609 (2017). 27792866

Health Report

Examination Date / Room / Rack2023/07/26Room:3-CRack:FAdditional tests
2023/07/24Room:3-CRack:FSentinel mouse program
2023/04/24Room:3-CRack:FSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
EGFP Enhanced Green Fluorescent Protein (Aequorea victoria)UNEGFP CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
TAp63c transformation related protein 63UNTAp63c
loxP phage P1 loxPUNloxP
loxP phage P1 loxPUNloxP
SV40 polyAUN

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Bacteriophage P1 loxP sites, Jellyfish EGFP cDNA, Avitag (biotin acceptor peptide), 3xFLAG tag, Mouse TAp63c gene cDNA
Research applicationCre/loxP system
Fluorescent Proteins/lacZ System
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Arthritis Rheumatol. 2017 Mar;69(3):598-609. doi: 10.1002/art.39976.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorTaku Saito (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. CAGGS MTA (English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data