Strain Data Sheet

RBRC10961

Strain Information

Image
BRC No.RBRC10961
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6.Cg-Pbwg1/24Nga-Lyst<bg-Nga>
Former Common nameB6. Cg-Pbwgl/24Nga-Lyst bg-N
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Akira Ishikawa, Graduate School of Bioagricultural Science, Nagoya University in 2017.
Strain descriptionThis allele is defined by a noncomplementation test with C57BL/6JHamSlc-Lystbg. This mutation is the result of a 4 bp deletion in Lyst exon 29 that produced frameshift mutations resulting in 3 amino-acid substitutions and creation of 6 new stop codons. The sequence data was deposited in DDBJ under Accession number LC508235.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Lyst
MGI:107448		lysosomal trafficking regulator13Lyst<bg-Nga>
MGI:6378151		lysosomal trafficking regulator; beige Nagoya
  • Chediak-Higashi syndrome(DisGeNET, MedGEN)
    • Pbwg1
    MGI:3035957    		postnatal body weight growth 12Pbwg1 postnatal body weight growth 1

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationMouse Models for Human Disease
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of its use with the DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. In publishing the research results obtained b use of the BIOLOGICAL RESOURCE, a citation of the MGI ID 6378151 (https://www.informatics.jax.org/allele/MGI:6378151) designated by the DEPOSITOR is requested.
    DepositorAkira Ishikawa (Nagoya University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data