Strain Data Sheet

RBRC11203

Strain Information

Image
BRC No.RBRC11203
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6-Rora<tm1.1Shkm>
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Shigeo Koyasu in 2021. This strain was generated using B6JN/1 ES cells. The neo gene cassette was removed by crossing to B6;SJL-Tg(ACTFLPE)9205Dym/J.
Strain descriptionFloxed Rora mice. A pair of loxP flanks exon 3 of the Rora gene.
Colony maintenance
References
Bacteria-Induced Group 2 Innate Lymphoid Cells in the Stomach Provide Immune Protection through Induction of IgA.
Satoh-Takayama N, Kato T, Motomura Y, Kageyama T, Taguchi-Atarashi N, Kinoshita-Daitoku R, Kuroda E, Di Santo J P, Mimuro H, Moro K, Ohno H
Immunity, 52, 635-649 (2020). 32240600

Health Report

Examination Date / Room / Rack2023/11/20Room:4-ARack:DSentinel mouse program
2023/08/21Room:4-ARack:DSentinel mouse program
2023/05/22Room:4-ARack:DSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site9Frt
Rora
MGI:104661		RAR-related orphan receptor alpha9Rora<tm1.1Shkm> targeted mutation 1.1, Shigeo Koyasu
  • intellectual developmental disorder with or without epilepsy or cerebellar ataxia(MedGEN)
    • loxP phage P1 loxP9loxP
    loxP phage P1 loxP9loxP

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAphage P1 loxP sites, Saccharomyces cerevisiae Flp recombination Target site (FRT), mouse Rora genomic DNA
    Research applicationCre/loxP system
    FLP/frt system
    Immunology and Inflammation Research
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorShigeo Koyasu (RIKEN)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data