Strain Data Sheet
RBRC11291
Strain Information | |
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| Image | |
| BRC No. | RBRC11291 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6.129-Lyn<tm1Tya> |
| Former Common name | |
| H-2 Haplotype | |
| ES Cell line | E14 [129P2/OlaHsd] |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Tadashi Yamamoto, OIST, in 2021. E14 ES Cells were used to generate this strain. Mice were further backcrossed to C57BL/6J for 7 or 8 generations. C57BL/6 congenicc strain. |
| Strain description | Lyn knockout mice. Exon 4 of the Lyn gene was replaced with a neo gene. |
| Colony maintenance | |
| References | Immunity, 3, 549-60 (1995). 7584145 J. Immunol., 158, 2350-2355 (1997). 9036984 J. Exp. Med., 187, 1343-1348 (1998). 9547345 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (Bovine)4GH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)4mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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| Donor DNA | 大腸菌 Neo, マウス PGK-promoter, ウシ growth hormone polyA付 |
| Research application | |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Immunity 3, 549-60 (1995). |
| Depositor | Tadashi Yamamoto (Okinawa Institute of Science and Technology Graduate University (OIST)) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |