Strain Information | |
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Image | |
BRC No. | RBRC11295 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129-Nyap1<tm1Tya> Nyap2<tm1Tya> Myo16<tm1Tya> |
Former Common name | Nyap1/2/3 triple KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Tadashi Yamamoto, OIST, in 2021. E14.1 ES Cells were used to generate this strain. Mice were further backcrossed to C57BL/6J for 7 or 8 generations. C57BL/6 congenicc strain. |
Strain description | Triple knockouf mice for Nyap1, Nyap2, Nyap3 (Myo16). |
Colony maintenance | |
References | EMBO J., 30 (23) 4739-54 (2011). 21946561 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Nyap2neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 21Nyap2<tm1Tya>targeted mutation 1, Tadashi Yamamoto Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Nyap1neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 15Nyap1<tm1Tya>targeted mutation 1, Tadashi Yamamoto Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (Bovine)GH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | 大腸菌 Neo, ファージ loxP, マウス PGK-promoter, ウシ growth hormone polyA付 |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J., 30 (23) 4739-54 (2011). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Tadashi Yamamoto (Okinawa Institute of Science and Technology Graduate University (OIST)) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |