Strain Data Sheet
RBRC11296
Strain Information | |
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| Image | |
| BRC No. | RBRC11296 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6;129-Ptpn4<tm1Tya> |
| Former Common name | PTPMEG |
| H-2 Haplotype | |
| ES Cell line | E14 [129P2/OlaHsd] |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Tadashi Yamamoto, OIST, in 2021. E14 ES Cells were used to generate this strain. Mice were further backcrossed to C57BL/6J for 3 generations. |
| Strain description | A reporter mice for the Ptpn4 gene, in which Tau-LacZ was inserted at the translation initiation codon. |
| Colony maintenance | |
| References | Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression. Kina S, Tezuka T, Kusakawa S, Kishimoto Y, Kakizawa S, Hashimoto K, Ohsugi M, Kiyama Y, Horai R, Sudo K, Kakuta S, Iwakura Y, Iino M, Kano M, Manabe T, Yamamoto T Eur. J. Neurosci., 26 (8) 2269-78 (2007). 17953619 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| GH | Growth hormone polyA (Bovine) | 1 | GH | ||||
| Ptpn4 MGI:1099792 | protein tyrosine phosphatase, non-receptor type 4 | 1 | Ptpn4<tm1Tya> MGI:3764684 | targeted mutation 1, Tadashi Yamamoto | |||
| lacZ | beta-galactosidase (E. coli) | 1 | |||||
| loxP | phage P1 loxP | 1 | loxP | ||||
| neo | neomycin resistance gene (E. coli) | 1 | |||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | マウス PGK-promoter, ウシ growth hormone polyA付, tau, 大腸菌 Neo, LacZ, P1 phage loxP |
| Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
| Specific Term and Conditions | |
| Depositor | Tadashi Yamamoto (Okinawa Institute of Science and Technology Graduate University (OIST)) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |