Strain Data Sheet
RBRC11306
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11306 |
| Type | CRISPR/Cas9 |
| Species | Mus musculus |
| Strain name | C3-Mpst<em1Rmps> |
| Former Common name | Mpst KO mouse |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Takeo Yoshikawa, RIKEN in 2021. C3H genetic background. |
| Strain description | Mpst knockout mice |
| Colony maintenance | |
| References | Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology. Ide M, Ohnishi T, Toyoshima M, Balan S, Maekawa M, Shimamoto-Mitsuyama C, Iwayama Y, Ohba H, Watanabe A, Ishii T, Shibuya N, Kimura Y, Hisano Y, Murata Y, Hara T, Morikawa M, Hashimoto K, Nozaki Y, Toyota T, Wada Y, Tanaka Y, Kato T, Nishi A, Fujisawa S, Okano H, Itokawa M, Hirokawa N, Kunii Y, Kakita A, Yabe H, Iwamoto K, Meno K, Katagiri T, Dean B, Uchida K, Kimura H, Yoshikawa T EMBO Mol. Med., 11(12):e10695 (2019). 31657521 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Mpst MGI:2179733 | mercaptopyruvate sulfurtransferase | 15 | Mpst<em1Rmps> MGI:6405753 | endonuclease-mediated mutation 1, Takeo Yoshikawa | |||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | Streptococcus Pyogenes Cas9 nickase* (* Not detected by PCR using Marker Gene Detection kit (TOYOBO, Osaka, Japan). ) |
| Research application | Mouse Models for Human Disease |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO Mol. Med., 11(12):e10695 (2019). |
| Depositor | Takeo Yoshikawa (RIKEN CBS) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |