Strain Data Sheet

RBRC11311

Strain Information

Image
BRC No.RBRC11311
TypeChemically-induced Mutation
SpeciesMus musculus
Strain nameB6N.B6J-Impa1<Rgsc01846>/Rmps
Former Common nameImpa1 T95K mouse
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Tekeo Yoshikawa, RIKEN in 2021. C57BL/6N congenic line.
Strain descriptionMutant mouse strain established by RIKEN ENU-based gene-driven mutagenesis. Gene: Impa1, Substitution: C→A Type: Thr > Lys
Colony maintenance
References
Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis.
Ohnishi T, Murata T, Watanabe A, Hida A, Ohba H, Iwayama Y, Mishima K, Gondo Y, Yoshikawa T
J. Biol. Chem., 289, 10785-96 (2014). 24554717

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Impa1
MGI:1933158		inositol (myo)-1(or 4)-monophosphatase 13Impa1<Rgsc01846>
MGI:6469955		RIKEN Genomic Sciences Center (GSC), 01846
  • intellectual disability, autosomal recessive 59(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationMouse Models for Human Disease
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 289, 10785-96 (2014). The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
    DepositorTakeo Yoshikawa (RIKEN CBS)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data