Strain Information | |
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Image | |
BRC No. | RBRC11326 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | Blimp1-floxed mice, B6.Cg-Prdm1<tm2Masu>/Dkit |
Former Common name | Blimp1fl, Blimp1 loxP, Blimp1(Prdm1)-floxed mouse |
H-2 Haplotype | |
ES Cell line | E14.1 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Deposited by Alexander Tarakhovsky, Rockefeller University in 2021. This strain was generated using E14.1 ES cells derived from 129P2/OlaHsd and then backcrossed to C57BL/6N. |
Strain description | Floxed Blimp1 (Prdm1) mouse. A pair of loxP flanks exon 5. A neo cassette was removed in this strain. |
Colony maintenance | |
References | Blimp1 is a critical determinant of the germ cell lineage in mice. Ohinata Y, Payer B, O'Carroll D, Ancelin K, Ono Y, Sano M, Barton S C, Obukhanych T, Nussenzweig M, Tarakhovsky A, Saitou M, Surani M A Nature, 436 (7048) 207-13 (2005). 15937476 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Prdm1 | PR domain containing 1, with ZNF domain | 10 | Prdm1 | targeted mutation 2, M Azim Surani | |||
loxP | phage P1 loxP | 10 | loxP | ||||
loxP | phage P1 loxP | 10 | loxP |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | P1 phage loxP sites, Mouse Prdm1 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to the RECIPIENT at a not-for-profit institution for academic, non-commercial research. If the RECIPIENT of the BIOLOGICAL RESOURCE desires to use or license the BIOLOGICAL RESOURCE for COMMERCIAL PURPOSES(as defined below), the RECIPIENT is required in advance of such use, to negotiate in good faith with the DEPOSITOR to establish the terms of a commercial license. "COMMERCIAL PURPOSES" means the sale, lease license, or other transfer of the BIOLOGICAL RESOURCE to a for-profit organization. COMMERCIAL PURPOSES shall also include uses of the BIOLOGICAL RESOURCE by any or organization, including the RIKEN BRC, to perform contract research, to screen compound libraries, to produce or manufacture products for general sale, or to conduct research activities that result in any sale, lease license, or transfer of the BIOLOGICAL RESOURCE to a for-profit organization. |
Depositor | Alexander Tarakhovsky (The Rockefeller University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |