Strain Data Sheet

RBRC11335

Strain Information

Image
BRC No.RBRC11335
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain namePpp6c (Acc.No.CDB0850K)
Former Common namePpp6c (Acc.No.CDB0850K)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Abrogation of protein phosphatase 6 promotes skin carcinogenesis induced by DMBA.
K Hayashi, Y Momoi, N Tanuma, A Kishimoto, H Ogoh, H Kato, M Suzuki, Y Sakamoto, Y Inoue, M Nomura, H Kiyonari, M Sakayori, K Fukamachi, Y Kakugawa, Y Yamashita, S Ito, I Sato, A Suzuki, M Nishio, M Suganuma, T Watanabe, H Shima
Oncogene, 34(35):4647-55 (2015). 25486434

Health Report

Examination Date / Room / Rack2024/12/09Room:3-6Rack:BSentinel mouse program
2024/09/09Room:3-6Rack:BSentinel mouse program
2024/06/10Room:3-6Rack:BSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site2Frt
Frt yeast FRT (flippase recombination target) site2Frt
Ppp6c
MGI:1915107
protein phosphatase 6, catalytic subunit2Ppp6c<tm1Shma> targeted mutation 1, Hiroshi Shima
loxP phage P1 loxP2loxP
loxP phage P1 loxP2loxP
neo neomycin resistance gene (E. coli)2 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAphage P1 loxP sites, yeast FRT (flippase recombination target) sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neomycin resistance gene, mouse PGK 3’end, mouse Ppp6c genomic DNA
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 34(35):4647-55 (2015). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is restricted to a RECIPIENT of a not-for organization for a not-for-profit research. The RECIPIENT shall obtain a prior agreement from the DEVELOPER(Hiroshi Shima Shima@med.tohoku.ac.jp) to transfer the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit organization or by a not-for profit organization for a for-profit research, the RECIPIENT must reach agreement on Terms and Conditions of use of it with the DEPOSITOR (mutant.bdr@riken.jp) and must obtain a prior written consent from the DEPOSITOR. Please inform the DEPOSITOR about the paper when published.
DepositorHiroshi Kiyonari (RIKEN BDR)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data