Strain Data Sheet

RBRC11336

Strain Information

Image
BRC No.RBRC11336
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain namePKN3 (-) (Acc.No.CDB0457K)
Former Common namePKN3 (-) (Acc.No.CDB0457K)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
PKN3 is the major regulator of angiogenesis and tumor metastasis in mice.
Mukai H, Muramatsu A, Mashud R, Kubouchi K, Tsujimoto S, Hongu T, Kanaho Y, Tsubaki M, Nishida S, Shioi G, Danno S, Mehruba M, Satoh R, Sugiura R
Sci. Rep., 6:18979 (2016). 26742562

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frt yeast FRT (flippase recombination target) site2Frt
Pkn3
MGI:2388285		protein kinase N32Pkn3
loxP phage P1 loxP2loxP
neo neomycin resistance gene (E. coli)2 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNANeo：大腸菌由来、loxP：P1ﾌｧｰｼﾞ由来、PGKプロモーター,PGK 3’end：マウス由来
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci. Rep., 6:18979 (2016). doi: 10.1038/srep18979.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is restricted to a RECIPIENT of a not-for organization for a not-for-profit research. The RECIPIENT shall obtain a prior agreement from the DEVELOPER(Hideyuki Mukai mukinase@kobe-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit organization or by a not-for profit organization for a for-profit research, the RECIPIENT must reach agreement on Terms and Conditions of use of it with the DEPOSITOR (mutant.bdr@riken.jp) and must obtain a prior written consent from the DEPOSITOR. Please inform the DEPOSITOR about the paper when published.
DepositorHiroshi Kiyonari (RIKEN BDR)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data