Strain Data Sheet

RBRC11341

Strain Information

Image
BRC No.RBRC11341
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain namemDia2 (Acc No. CDB0419K)
Former Common namemDia2 (Acc No. CDB0419K)
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis.
Sadanori Watanabe, Tihana De Zan, Toshimasa Ishizaki, Shingo Yasuda, Hiroshi Kamijo, Daisuke Yamada, Tomohiro Aoki, Hiroshi Kiyonari, Hiroshi Kaneko, Ritsuko Shimizu, Masayuki Yamamoto, Gohta Goshima, Shuh Narumiya
Cell Rep., 5(4):926-32 (2013). 24239357

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Diaph3
MGI:1927222		diaphanous related formin 314Diaph3<tm1.1Sna>
MGI:5574347		targeted mutation 1.1, Shuh Narumiya
  • autosomal dominant auditory neuropathy 1(MedGEN)
    • loxP phage P1 loxP14loxP

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAloxP：P1ﾌｧｰｼﾞ由来
    Research applicationCre/loxP system
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Rep., 5(4):926-32 (2013).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is restricted to a RECIPIENT of a not-for organization for a not-for-profit research. The RECIPIENT shall obtain a prior agreement from the DEVELOPER(Shuh Narumiya snaru@mfour.med.kyoto-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit organization or by a not-for profit organization for a for-profit research, the RECIPIENT must reach agreement on Terms and Conditions of use of it with the DEPOSITOR (mutant.bdr@riken.jp) and must obtain a prior written consent from the DEPOSITOR. Please inform the DEPOSITOR about the paper when published.
    DepositorHiroshi Kiyonari (RIKEN BDR)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data