Strain Information | |
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Image | |
BRC No. | RBRC11344 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | CNOT6 (loxP)(Acc No.CDB0794K) |
Former Common name | CNOT6 (loxP)(Acc No.CDB0794K) |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability. Dina Mostafa, Akinori Takahashi, Akiko Yanagiya, Tomokazu Yamaguchi, Takaya Abe, Taku Kureha, Keiji Kuba, Yumi Kanegae, Yasuhide Furuta, Tadashi Yamamoto, Toru Suzuki RNA Biol., 17(3):403-416 (2020). 31924127 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Cnot6 MGI:2144529 | CCR4-NOT transcription complex, subunit 6 | 11 | Cnot6<tm1Tya> | targeted mutation 1, Tadashi Yamamoto | |||
Frt | yeast FRT (flippase recombination target) site | 11 | Frt | ||||
loxP | phage P1 loxP | 11 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 11 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Neo:大腸菌由来、loxP:P1ファージ由来、frt:酵母菌由来、PGKプロモーター,PGK 3’end:マウス由来 |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. RNA Biol., 17(3):403-416 (2020).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is restricted to a RECIPIENT of a not-for organization for a not-for-profit research. The RECIPIENT shall obtain a prior agreement from the DEVELOPER(Yamamoto Tadashi tadashi.yamamoto@oist.jp) to transfer the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit organization or by a not-for profit organization for a for-profit research, the RECIPIENT must reach agreement on Terms and Conditions of use of it with the DEPOSITOR (mutant.bdr@riken.jp) and must obtain a prior written consent from the DEPOSITOR. Please inform the DEPOSITOR about the paper when published. |
Depositor | Hiroshi Kiyonari (RIKEN BDR) |
Strain Status | ![]() |
Strain Availability | ![]() |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |