Strain Data Sheet

RBRC11344

Strain Information

Image
BRC No.RBRC11344
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameCNOT6 (loxP)(Acc No.CDB0794K)
Former Common nameCNOT6 (loxP)(Acc No.CDB0794K)
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability.
Dina Mostafa, Akinori Takahashi, Akiko Yanagiya, Tomokazu Yamaguchi, Takaya Abe, Taku Kureha, Keiji Kuba, Yumi Kanegae, Yasuhide Furuta, Tadashi Yamamoto, Toru Suzuki
RNA Biol., 17(3):403-416 (2020). 31924127

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cnot6
MGI:2144529
CCR4-NOT transcription complex, subunit 611Cnot6<tm1Tya> targeted mutation 1, Tadashi Yamamoto
Frt yeast FRT (flippase recombination target) site11Frt
loxP phage P1 loxP11loxP
neo neomycin resistance gene (E. coli)11 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNANeo:大腸菌由来、loxP:P1ファージ由来、frt:酵母菌由来、PGKプロモーター,PGK 3’end:マウス由来
Research applicationCre/loxP system
FLP/frt system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. RNA Biol., 17(3):403-416 (2020).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is restricted to a RECIPIENT of a not-for organization for a not-for-profit research. The RECIPIENT shall obtain a prior agreement from the DEVELOPER(Yamamoto Tadashi tadashi.yamamoto@oist.jp) to transfer the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit organization or by a not-for profit organization for a for-profit research, the RECIPIENT must reach agreement on Terms and Conditions of use of it with the DEPOSITOR (mutant.bdr@riken.jp) and must obtain a prior written consent from the DEPOSITOR. Please inform the DEPOSITOR about the paper when published.
DepositorHiroshi Kiyonari (RIKEN BDR)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data