Strain Data Sheet
RBRC11357
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11357 |
| Type | CRISPR/Cas9 |
| Species | Mus musculus |
| Strain name | B6.B6D2-H2ax<em1Ibbr> |
| Former Common name | H2A.X<+/-> |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Dai Tsukioka and Fugaku Aoki, The University of Tokyo, in 2021. Mice were generated using fertilized eggs derived from BDF1 with the CRISPR/Cas9. Mice were backcrossed to C57BL/6J for six generation. C57BL/6 congenic strain. Homozygous males are infertile, whereas homozygous females deliver smaller number of pups. |
| Strain description | H2ax mutant mouse generated by the CRISPR/Cas9. 38 bp deletion in the H2ax gene. |
| Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
| References | |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| H2ax MGI:102688 | H2A.X variant histone | 9 | H2ax<em1Ibbr> | endonuclease-mediated mutation 1, Fugaku Aoki | |||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | |
| Research application | |
| Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
| Depositor | Fugaku Aoki (The University of Tokyo) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
|---|
| No Data |