Strain Data Sheet

RBRC11359

Strain Information

Image
BRC No.RBRC11359
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Sall1<tm1Ryn>
Former Common nameSall1-del
H-2 Haplotype
ES Cell lineCCE [129/Sv]
Background strain
Appearance
Strain developmentDeposited by Ryuichi Nishinakamura, Kumamoto University in 2021. This strain was generated using CCE/EK.CCE (ES Cell) derived from 129S/SvEv-Gpi1<c>. Mice were further backcrossed to C57BL/6J for 5 generations.
Strain descriptionSall1 knockout mice. Homozygous mutant die perinatally due to kidney agenesis.
Colony maintenance
References
Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development.
Nishinakamura R, Matsumoto Y, Nakao K, Nakamura K, Sato A, Copeland N G, Gilbert D J, Jenkins N A, Scully S, Lacey D L, Katsuki M, Asashima M, Yokota T
Development, 128(16):3105-15 (2001). 11688560

Zinc finger protein sall2 is not essential for embryonic and kidney development.
Sato A, Matsumoto Y, Koide U, Kataoka Y, Yoshida N, Yokota T, Asashima M, Nishinakamura R
Mol. Cell. Biol., 23(1):62-9 (2003). 12482961

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Sall1
MGI:1889585		spalt like transcription factor 18Sall1<tm1Ryn>
MGI:2388379		targeted mutation 1, Ryuichi Nishinakamura
  • Townes-Brocks syndrome 1(MedGEN)

  • Townes-Brocks syndrome(DisGeNET)
    • neo neomycin resistance gene (E. coli)8 mouse phosphoglycerate kinase promoter (PGK promoter)

    Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAマウス PGK プロモーター, 大腸菌 Neo 耐性遺伝子
    Research applicationDevelopmental Biology Research
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 128(16):3105-15 (2001).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit organization or commercial users, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of a application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorRyuichi Nishinakamura (Kumamoto University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data