Strain Data Sheet

RBRC11363

Strain Information

Image
BRC No.RBRC11363
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameC57BL/6N-Abca13<em1Kueda>
Former Common nameAbca13KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Kazumitsu Ueda, Kyoto University in 2021. C57BL/6N genetic background.
Strain descriptionAbca13 mutant mouse generated by the CRISPR/Cas9. 83 bp deletion in the Abca13 gene.
Colony maintenance
References
ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking.
Nakato M, Shiranaga N, Tomioka M, Watanabe H, Kurisu J, Kengaku M, Komura N, Ando H, Kimura Y, Kioka N, Ueda K
J. Biol. Chem., Dec 16;296:100166 (2020). 33478937

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Abca13
MGI:2388707		ATP-binding cassette, sub-family A member 1311Abca13<em1Kueda> endonuclease-mediated mutation 1, Kazumitsu Ueda

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAmouse Abca13 gene (20 bp)
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 296, 100166 (2020).
DepositorKazumitsu Ueda (Kyoto University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data