Strain Data Sheet

RBRC11381

Strain Information

Image
BRC No.RBRC11381
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameC57BL/6-Proc<em1Tsuka>
Former Common nameProc knockout mice(CRISPR/Cas9)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Tsukasa Ohmori, Jichi Medical University in 2021. C57BL/6J genetic background.
Strain descriptionProc mutant mice generated by the CRISPR/Cas9. 1 bp deletion and 2 bp insertion at exon 9 of the Proc gene. Homozygous mutants are perinatally lethal.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Proc
MGI:97771		protein C18Proc<em1Tsuka> endonuclease-mediated mutation 1, Tsukasa Ohmori
  • thrombophilia due to protein C deficiency, autosomal dominant(MedGEN)

  • thrombophilia due to protein C deficiency, autosomal recessive(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
    DepositorTsukasa Ohmori (Jichi Medical University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data