Strain Data Sheet

RBRC11394

Strain Information

Image
BRC No.RBRC11394
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameC57BL/6J-Was<em1(I292T)Imsmt>
Former Common nameWASp-I292T
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Arinobu Tojo in 2021. C57BL/6J genetic background genretated by the CRISPR/Cas9 technique.
Strain descriptionWas mutant mouse harboring I292T mutation corresponding to human WASp-I290T mutation.
Colony maintenance
References

Health Report

Examination Date / Room / Rack2023/10/10Room:3-BRack:KSentinel mouse program
2023/07/10Room:3-BRack:KSentinel mouse program
2023/06/26Room:3-BRack:KAdditional tests
2023/06/26Room:3-BRack:KAdditional tests
2023/04/10Room:3-BRack:KSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Was
MGI:105059		Wiskott-Aldrich syndromeXWas<em1(I292T)Imsmt> endonuclease mediated mutation 1,
  • thrombocytopenia 1(DisGeNET, MedGEN)

  • Wiskott-Aldrich syndrome(DisGeNET, MedGEN)

  • X-linked severe congenital neutropenia(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationMouse Models for Human Disease
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorArinobu TOJO (The University of Tokyo)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data