Strain Data Sheet

RBRC11395

Strain Information

Image
BRC No.RBRC11395
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain name129S6/SvEv-Samd7<tm1Tfur>
Former Common nameSamd7 KO
H-2 Haplotype
ES Cell lineTC1 [129S6/SvEvTac]
Background strain
Appearance
Strain developmentDeposited by Takahisa Furukawa, Osaka University in 2021. This strain was generated using TC1/TC-1 (ES Cell) derived from 129S6/SvEvTac. 129S6 genetic background.
Strain descriptionKncokout mice for Samd7. Exon 4 to 6 of the Samd7 gene were deleted.
Colony maintenance
References
Arresting dissolution by interfacial rheology design.
Beltramo P J, Gupta M, Alicke A, Liascukiene I, Gunes D Z, Baroud C N, Vermant J
Proc. Natl. Acad. Sci. USA, 114(39):E8246-E8273 (2017). 28893993

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Samd7
MGI:1923203		sterile alpha motif domain containing 73Samd7<tm1Tfur>
MGI:6150316		targeted mutation 1, Takahisa Furukawa
loxP phage P1 loxP3loxP
loxP phage P1 loxP3loxP
neo neomycin resistance gene (E. coli)3 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAphage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neomycin resistance gene, mouse Samd7 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc Natl Acad Sci USA. 2017 Sep 26;114(39):E8246-E8273Prior to the requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contact the DEPOSITOR and contract an MTA with Osaka University.
DepositorTakahisa Furukawa (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data