Strain Data Sheet

RBRC11422

Strain Information

Image
BRC No.RBRC11422
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6-Cyp4f39<em1Akih>
Former Common nameCyp4f39 KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Akio Khara in 2021. Mice were generated using C57BL/6J with the CRISPR/Cas9. C57BL/6J genetic background.
Strain descriptionCyp4f39 mutant mice. 32 bp insertion at exon 11 of the Cyp4f39 gene.
Colony maintenance
References
Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid omega-Hydroxylase Crucial to Acylceramide Production.
Miyamoto M, Itoh N, Sawai M, Sassa T, Kihara A
J. Invest. Dermatol.,140,319-326 (2020). 31356814

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cyp4f39
MGI:2445210		cytochrome P450, family 4, subfamily f, polypeptide 3917Cyp4f39<em1Akih>
MGI:6423306		endonuclease-mediated mutation 1, Akio Kihara
  • autosomal recessive congenital ichthyosis 5(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorAkio Kihara (Hokkaido University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data