Strain Information | |
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Image | |
BRC No. | RBRC11441 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129P2-Kdm6b<tm1.1Masn> |
Former Common name | 129B6-Jmjd3(Kdm6b) kncokout mice |
H-2 Haplotype | |
ES Cell line | E14.1 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Deposited by Masahide Asano, Kyoto University in 2021. This strain was generated using E14 ES cells derived from 129P2/OlaHsd and then mice were crossed to C57BL/6J once. Mixed genetic background. |
Strain description | Jmjd3(Kdm6b)knockout mice lacking exon 18 of the Jmjd3(Kdm6b) gene. Homozygous mutant are neonatally lethal. |
Colony maintenance | |
References | FASEB J., 31(6):2252-2266 (2017). doi: 10.1096/fj.201600642R. 28188179 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site11Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Iresinternal ribosomal entry site (EMCV)11 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP11loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11 |
Ordering Information | |
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Donor DNA | Bacteriophage P1 loxP sites, Saccharomyces cerevisiae FRT sites, Mouse En-2 splicing acceptor, encephalomyocarditis virus Internal ribosomal entry site, E. coli Neomycin resistant gene, Bovine polyA signal |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. FASEB J., 31(6):2252-2266 (2017). doi: 10.1096/fj.201600642R.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT must contact the DEPOSITOR in the case of a application for an patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Masahide Asano and Dr. Chie Naruse is requested. (Contact info: Dr. Masahide Asano <asano@anim.med.kyoto-u.ac.jp>, Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University) |
Depositor | Masahide Asano (Kyoto University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |