Strain Data Sheet
RBRC11446
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11446 |
| Type | CRISPR/Cas9 |
| Species | Mus musculus |
| Strain name | C57BL/6J-Lamp5<em1Atai> |
| Former Common name | Lamp5 KO |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Atsu Aiba, The University of Tokyo in 2021. C57BL/6J genetic background. Homozygous mutants look normal. |
| Strain description | Mutant mic lacking a genomic region of the Lamp5 from exon 2 to intron 5. |
| Colony maintenance | |
| References | LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing. Koebis M, Urata S, Shinoda Y, Okabe S, Yamasoba T, Nakao K, Aiba A, Furuichi T Mol. Brain, 12(1):20 (2019). 30867010 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Lamp5 MGI:1923411 | lysosomal-associated membrane protein family, member 5 | 2 | Lamp5<em1Atai> MGI:6449112 | endonuclease-mediated mutation 1, | |||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | Streptococcus pyogenes SpCas9 (human codon-optimized), Syntheticsg RNA |
| Research application | |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Brain, 12(1):20 (2019). |
| Depositor | Atsu Aiba (The University of Tokyo) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |