Strain Data Sheet

RBRC11511

Strain Information

Image
BRC No.RBRC11511
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6.C3H-In(6)1J Mitf<em1Chuan>
Former Common nameB6.C3H-In(6)1J Mitf<em1Cu>
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Takashi Iwamoto Chubu University in 2021.
Strain descriptionMitf mutant with In(6)1J derived from C3H/HeJ.
Colony maintenance
References
An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain.
Satoru Iwata, Takahisa Sasaki, Miki Nagahara, Takashi Iwamoto
G3 (Bethesda),11(8):jkab194(2021). 34849815

An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain.
Iwata S, Sasaki T, Nagahara M, Iwamoto T
G3 (Bethesda),11(8):jkab194(2021). 34849815

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Mitf
MGI:104554		melanogenesis associated transcription factor6Mitf<em1Chuan> endonuclease-mediated mutation 1,
  • coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness(MedGEN)

  • melanoma, cutaneous malignant, susceptibility to, 8(MedGEN)

  • Tietz syndrome(DisGeNET, MedGEN)
    • more 2 Diseases
  • Waardenburg syndrome type 2(DisGeNET)

  • Waardenburg syndrome type 2A(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genetics Society of America　https://doi.org/10.1093/g3journal/jkab194
    DepositorTakashi Iwamoto (Chubu University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data