Strain Data Sheet

RBRC11511

Strain Information

Image
BRC No.RBRC11511
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6.C3H-In(6)1J Mitf<em1Chuan>
Former Common nameB6.C3H-In(6)1J Mitf<em1Cu>
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Takashi Iwamoto Chubu University in 2021.
Strain descriptionMitf mutant with In(6)1J derived from C3H/HeJ.
Colony maintenance
References
An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain.
Satoru Iwata, Takahisa Sasaki, Miki Nagahara, Takashi Iwamoto
G3 (Bethesda),11(8):jkab194(2021). 34849815

An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain.
Iwata S, Sasaki T, Nagahara M, Iwamoto T
G3 (Bethesda),11(8):jkab194(2021). 34849815

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Mitf
MGI:104554		melanogenesis associated transcription factor6Mitf<em1Chuan> endonuclease-mediated mutation 1,
  • coloboma, osteopetrosis, microphthalmia, macrocephaly, albinism, and deafness(MedGEN)

  • melanoma, cutaneous malignant, susceptibility to, 8(MedGEN)

  • Tietz syndrome(DisGeNET, MedGEN)
    • more 2 Diseases
  • Waardenburg syndrome type 2A(DisGeNET, MedGEN)

  • Waardenburg syndrome type 2(DisGeNET)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genetics Society of America　https://doi.org/10.1093/g3journal/jkab194
    DepositorTakashi Iwamoto (Chubu University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data