Strain Information | |
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Image | |
BRC No. | RBRC11522 |
Type | CRISPR/Cas9 (Transgene)![]() |
Species | Mus musculus |
Strain name | B6-Cd19<tm1.1(icre)Yoba> |
Former Common name | CD19-iCre |
H-2 Haplotype | |
ES Cell line | EGR-101 [C57BL/6N] |
Background strain | |
Appearance | |
Strain development | Deposited by Yoshihiro Baba, Kyushu University in 2021. C57BL/6 genetic background. |
Strain description | iCre knockin mice at the Cd19 locus. T2A-iCre was inserted at stop codon. FRT-flanked neo gne was deleted. |
Colony maintenance | |
References | Generation and characterization of CD19-iCre mice as a tool for efficient and specific conditional gene targeting in B cells. Yasuda T, Saito Y, Ono C, Kawata K, Baba A, Baba Y Sci. Rep., 11(1):5524 (2021). 33750849 |
Health Report | |
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Examination Date / Room / Rack | 2025/01/07Room:3-ARack:JSentinel mouse program 2024/10/07Room:3-ARack:JSentinel mouse program 2024/04/08Room:3-ARack:JSentinel mouse program 2024/01/09Room:3-ARack:JSentinel mouse program 2023/10/10Room:3-ARack:JSentinel mouse program 2023/07/12Room:3-ARack:JAdditional tests 2023/07/10Room:3-ARack:JSentinel mouse program 2023/04/10Room:3-ARack:JSentinel mouse program |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Cd19 MGI:88319 | CD19 antigen | 7 | Cd19<tm1.1(icre)Yoba> | targeted mutation 1.1, Yoshihiro Baba | |||
Frt | yeast FRT (flippase recombination target) site | 7 | Frt | ||||
T2A | Thosea asigna virus 2A peptide (insect) | 7 | T2A | ||||
icre | phage P1 codon improved Cre (iCre) | 7 | icre |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Thosea asigna virus T2A, P1 phage iCre, Saccharomyces cerevisiae Frt site, mouse Cd19 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. RECIPIENT which wants to use the BIOLOGICAL RESOURCE is requested to contact the depositor (Dr. Yoshihiro Baba) and enter into a Material Transfer Agreement with Kyushu University. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
Depositor | Yoshihiro Baba (Kyushu University) |
Strain Status | ![]() ![]() ![]() |
Strain Availability | Cryopreserved sperm (within 1 month) Live mouse (1 to 3 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Jan 2023 |
BRC mice in Publications |
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No Data |