Strain Information | |
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Image | |
BRC No. | RBRC11524 |
Type | Targeted Mutation and Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Klb<tm1Yin> Tg(Alb-Klb/EGFP)5Yin |
Former Common name | KO bkl x Tg Alb-beta EGFP5 |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Deposited by Yo-ichi Nabeshima in 2021. C57BL/6 congenic strain. |
Strain description | Compound mice harboring Klb knockout and a transgene expressing Klb fused with EGFP under the control of Albumin promoter. |
Colony maintenance | |
References | J. Clin. Invest., 115(8):2202-8 (2005). 16075061 FASEB J., 30(2):849-62 (2016). 26514166 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EGFPEnhanced Green Fluorescent Protein (Aequorea victoria)5EGFP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)5mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EGFPEnhanced Green Fluorescent Protein (Aequorea victoria)UNEGFP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Klbklotho betaUNKlbmouse Albumin promoter, rabbit beta-globin intron Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 Poly A signalUN |
Ordering Information | |
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Donor DNA | mouse Phosphpglycerate kinase promoter, E. coli Neomycin resistance gene, mouse Albumin promoter, rabbit beta-globin intron, mouse beta-Klotho cDNA, jellyfish Enhanced green fluorescent protein cDNA, SV40 Poly A signal |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Clin. Invest., 115(8):2202-8 (2005). FASEB J., 30(2):849-62 (2016). |
Depositor | Yoichi Nabeshima (Foundation for Biomedical Research and Innovation at Kobe) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |