Strain Information | |
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Image | |
BRC No. | RBRC11551 |
Type | CRISPR/Cas9 |
Species | Mus musculus |
Strain name | B6-Ntrk1<em4Tkato>/KN9 |
Former Common name | B6J-Ntrk1 (CRISPR, KO); 13bΔ/+ |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Tadafumi Kato, RIKEN CBS in 2021. This strain was generated using the CRISPR/Cas9. C57BL/6J genetic background. |
Strain description | 13bp deletion at exon 12 of the Ntrk1 gene, which results in frame-shift with premature termination. |
Colony maintenance | |
References | Transl. Psychiatry, 10, 407 (2020). 33235206 Sci. Rep., 6:34703 (2016). 27698470 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Ntrk1neurotrophic tyrosine kinase, receptor, type 13Ntrk1<em4Tkato>endonuclease-mediated mutation 4, Tadafumi Kato |
Ordering Information | |
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Donor DNA | Streptococcus pyogenes Cas9 mRNA, Streptococcus pyogenes sgRNA, マウス single strand oligo DNA (a part of Ntrk1 gene) |
Research application | Mouse Models for Human Disease |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Transl. Psychiatry, 10, 407 (2020).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Tadafumi Kato (RIKEN) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |