Strain Data Sheet

RBRC11621

Strain Information

Image
BRC No.RBRC11621
TypeCRISPR/Cas9 (Transgene)Cartagena
SpeciesMus musculus
Strain nameC57BL/6J-Prdx4<em2Jufu>
Former Common namePrdx4t KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Junichi Fujii, Yamagata University in 2022. C57BL/6J background.
Strain descriptionPrdx4 mutant mice. This strain lacks Prdx4 transcript specific to testis.
Colony maintenance
References
Testis-specific peroxiredoxin 4 variant is not absolutely required for spermatogenesis and fertility in mice.
Takujiro Homma, Toshihiro Kurahashi, Naoki Ishii, Nobuyuki Shirasawa, Junichi Fujii
Sci. Rep., 10(1):17934 (2020). 33087733

Testis-specific peroxiredoxin 4 variant is not absolutely required for spermatogenesis and fertility in mice.
Homma T, Kurahashi T, Ishii N, Shirasawa N, Fujii J
Sci. Rep., 10(1):17934 (2020). 33087733

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Prdx4
MGI:1859815		peroxiredoxin 4XPrdx4<em2Jufu> endonuclease-mediated mutation 2, Junichi Fujii

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci Rep. 2020 Oct 21;10(1):17934. doi: 10.1038/s41598-020-74667-9.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorJunichi Fujii (Yamagata University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data