Strain Data Sheet
RBRC11670
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11670 |
| Type | CRISPR/Cas9 |
| Species | Mus musculus |
| Strain name | C57BL/6J-Rassf6<em1Kymt> |
| Former Common name | RASSF6 KO |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Kyoko Matsuzaki, Tokyo Medical and Dental University in 2022. C57BL/6J genetic background. |
| Strain description | Rassf6 mutant mice lacking whole exons. |
| Colony maintenance | |
| References | Characterization of mouse embryonic fibroblasts derived from Rassf6 knockout mice shows the implication of Rassf6 in the regulation of NF-κB signaling. Mayu Morishita, Kyoko Arimoto-Matsuzaki, Masami Kitamura, Kyohei Niimura, Hiroaki Iwasa, Junichi Maruyama, Yuichi Hiraoka, Kohei Yamamoto, Masanobu Kitagawa, Norio Miyamura, Hiroshi Nishina, Yutaka Hata Genes Cells., 26(12):999-1013 (2021). 34652874 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | 2024/04/08Room:3-ARack:JSentinel mouse program 2024/01/09Room:3-ARack:JSentinel mouse program 2023/10/10Room:3-ARack:JSentinel mouse program |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Rassf6 MGI:1920496 | Ras association (RalGDS/AF-6) domain family member 6 | 5 | Rassf6<em1Kymt> | endonuclease-mediated mutation 1, Kyoko Arimoto-Matsuzaki | |||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | mouse Rassf6 |
| Research application | Apoptosis Research Cancer Research Cell Biology Research Developmental Biology Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells., 26(12):999-1013 (2021). The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
| Depositor | Kyoko Matsuzaki (Tokyo Medical and Dental University) |
| Strain Status |  Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |