Strain Data Sheet
RBRC11675
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11675 |
| Type | CRISPR/Cas9 |
| Species | Mus musculus |
| Strain name | C57BL/6J-Mycl<em2Yasu> |
| Former Common name | MyclKO#949 |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Toshitada Hirano and depoisted by Yasuhiro Yamada, The University of Tokyo in 2022. C57BL/6J genetic background. |
| Strain description | Mycl mutant mice. Deletion and inversion of some portion of Exon 1 sequence. |
| Colony maintenance | |
| References | MYCL-mediated reprogramming expands pancreatic insulin-producing cells. Michitada Hirano, Yusei So, Shin Tsunekawa, Mio Kabata, Sho Ohta, Hiroshi Sagara, Nao Sankoda, Jumpei Taguchi, Yosuke Yamada, Tomoyo Ukai, Makoto Kato, Jiro Nakamura, Manabu Ozawa, Takuya Yamamoto, Yasuhiro Yamada Nat. Metab., 4(2):254-268 (2022). 35145326 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Mycl MGI:96799 | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived | 4 | Mycl<em2Yasu> | endonuclease-mediated mutation 2, Yasuhiro Yamada | |||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | |
| Research application | |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat Metab. 2022 Feb 10. doi: 10.1038/s42255-022-00530-y. |
| Depositor | Yasuhiro Yamada (The University of Tokyo) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |