Strain Data Sheet

RBRC11707

Strain Information

Image
BRC No.RBRC11707
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC.129X1(B6)-Pirb<tm1Ttk>
Former Common namePirB-KO mice
H-2 Haplotype
ES Cell lineRW4 [129X1/SvJ]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Impaired dendritic cell maturation and increased T(H)2 responses in PIR-B(-/-) mice.
Azusa Ujike, Kazuhiko Takeda, Akira Nakamura, Shin Ebihara, Kenichi Akiyama, Toshiyuki Takai
Nat. Immunol., 3(6):542-8 (2002). 12021780

Health Report

Examination Date / Room / Rack2024/11/25Room:4-BRack:ISentinel mouse program
2024/08/26Room:4-BRack:ISentinel mouse program
2024/05/27Room:4-BRack:ISentinel mouse program
2024/02/26Room:4-BRack:ISentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Pirb
MGI:894311		paired Ig-like receptor B7Pirb<tm1Ttk>
MGI:2180757		targeted mutation 1, Toshiyuki Takai
neo neomycin resistance gene (E. coli)7

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), Escherichia coli Neo, mouse Pirb genomic DNA
Research applicationImmunology and Inflammation Research
Neurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Immunol., 3(6):542-8 (2002). doi: 10.1038/ni801.
DepositorToshiyuki Takai (Tohoku University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityLive mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data