Strain Information | |
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Image | |
BRC No. | RBRC11712 |
Type | Targeted Mutation Congenic![]() |
Species | Mus musculus |
Strain name | B6;Cg-Sox2<tm1.1(cre/ERT2)Ykaw> |
Former Common name | Sox2 CreERT2 |
H-2 Haplotype | |
ES Cell line | V6.5 [(C57BL/6J x 129S4/SvJae)F1] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nao Sankoda, Wataru Tanabe, Akito Tanaka, Hirofumi Shibata, Knut Woltjen, Tsutomu Chiba, Hironori Haga, Yoshiharu Sakai, Masaki Mandai, Takuya Yamamoto, Yasuhiro Yamada, Shinji Uemoto, Yoshiya Kawaguchi Nat. Commun., 12(1):560 (2021). 33495473 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
ERT2 | estrogen receptor (ER), human ER with the triple mutation G400V/M543A/L544A) | 3 | ERT2 | ||||
Sox2 MGI:98364 | SRY (sex determining region Y)-box 2 | 3 | Sox2<tm1.1(cre/ERT2)Ykaw> | targeted mutation 1.1, Yoshiya Kawaguchi | |||
cre | Phage P1 Cre recombinase | 3 | cre |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | P1 Bacteriophage Cre, human Estrogen receptor binding domain (ERT2)cDNA, Rabbit (globin) (CreERT2-)pA, D6 Bacteriophage rox |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Commun., 12(1):560 (2021). doi: 10.1038/s41467-021-20906-0. 1) BIOLOGICAL RESOURCE must be used for academic research purpose conducted by the RECIPIENT who belongs to a non-profit academic organization, (i.e. a university or another institution of higher education or any non-profit scientific or educational organization, including government agencies.) 2) The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from KYOTO UNIVERSITY (Contact address: Contract Management Office, CiRA Foundation Email: cont-g@cira-foundation.or.jp). 3) The RECIPIENT must contact KYOTO UNIVERSITY (Contact address: Contract Management Office, CiRA Foundation Email: cont-g@cira-foundation.or.jp) in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Yoshiya Kawaguchi (Kyoto University) |
Strain Status | ![]() |
Strain Availability | ![]() |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |