Strain Information | |
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Image | |
BRC No. | RBRC11719 |
Type | Targeted Mutation![]() |
Species | Mus musculus |
Strain name | B6.129S-Vim<tm1Sibg> |
Former Common name | VIM<SA/SA> |
H-2 Haplotype | |
ES Cell line | EB3 [129/Ola] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells. Makoto Matsuyama, Hiroki Tanaka, Akihito Inoko, Hidemasa Goto, Shigenobu Yonemura, Kyoko Kobori, Yuko Hayashi, Eisaku Kondo, Shigeyoshi Itohara, Ichiro Izawa, Masaki Inagaki J. Biol. Chem., 288(50):35626-35 (2013). 24142690 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Vim MGI:98932 | vimentin | 2 | Vim<tm1Sibg> MGI:6355955 | targeted mutation 1, Shigeyoshi Itohara | |||
loxP | phage P1 loxP | 2 | loxP | ||||
loxP | phage P1 loxP | 2 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 2 |
Phenotype | |
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Phenotype annotation from literatures by Mammalian phenotype ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E.coli Neomycin resistant gene, mouse Vim genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 288(50):35626-35 (2013).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Masaki Inagaki is requested. |
Depositor | Daishi Yamakawa (Mie University) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |